Originally Posted by
Belleblue
Hi Nahdia, no I definitely don't think it's a sign that you are not getting a restful night's sleep - my sleep is the same as first time around.
Mirtazapine has a powerful anti-histamine effect as you probably know. Now the thing about anti-histamines is that they have a drying effect on the mucous membranes in our bodies... so I would say that this is what is causing the puffiness/dryness. You say you are only getting it for the first hour or so of the day, so that's not so bad.. try the remedies mentioned and in the meanwhile try not to dwell on it too much - it will probably disappear over time.
Belle x