I've been taking 45 mg of mirtazapine for close to 3 months now, with only a slight improvement in anxiety. My pdoc decided to augment this with 50 mg of sertraline. I've been sertaline by itself and the first few weeks were horrid - my anxiety went through the roof - before gradually abating.

I'm feeling a bit apprehensive about going through this phase again. Anybody added an SSRI to ongoing mirtazapine treatment and experience a worsening, or did the mirtazapine 'block' this from happening. I would really appreciate your inputs!