Guys I have been taking sertraline 50 for 6 weeks and I have been ill, I mean start up effects have never stopped, nausea, upset tum, shakes, increased anxiety, no appetite etc etc. I take omeprazole and this morning I didn’t, I realised that half an hour after taking my meds I didn’t have my normal bathroom dash and stomach pain. So I read the leaflet and it said there is an interaction. I then googled and omg omeprazole can double the sertraline level in your blood. I wanted to share incase anyone is like me and suffering and trying to figure out why their meds won’t settle, I may be jumping the gun and this may be a one off day of feeling good but I think it’s down to the omeprazole. Anyway, will see how it goes the next few days but right now I am so happy, I have been so exhausted with the side effects for such a long time.