Re: Why are SSRI’s too stimulating !!!!!!
Originally Posted by
SideFX
So all meds raise one or more level of neurotransmitters
Yes, usually beginning within about an hour of the first dose, however, after a week or two bio-feedback mechanisms come into play and reduce synthesis and expression which causes the affected neurotransmitter levels to drop dramatically in some regions of the brain associated with anxiety/depression.
and then downstream this encourages neurogenesis, which in turn creates healthy normal levels of neurones....
Not sure if the drop in neurotransmitter levels is the important factor, but it is certainly seems to be part of the process.
Thus recovery will be reached irrespective of the med, as long as it’s well tolerated ????
No AD is intrinsically better than the others, however, one or two will often prove more effective than the others for an individual. Some also respond better to noradrenaline/norepinephrine reuptake inhibitors (NRI) such as nortriptyline, desipramine and lofepramine than they do serotonin reuptake inhibitors. Unfortunately, these days many GPs and even some psychiatrists are barely aware they exist. Old time psychiatrists also favour supplementing a SSRI with a NRI over prescribing SNRIs. Not only can they essentially create a bespoke SNRI, but it avoids some of the SNRIs problems such as their short half-lives which can make both starting and stopping them difficult.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.