Thanks for your response PsychoPoet. I am not taking any other medications. After the restless sleep episodes I took a 3 month break from inositol and then read more on the positive effects of inositol on PCOS, and restarted it at 2g daily in the mornings. I haven't noticed any mood changes. I do notice I feel more tired/relaxed and ready for bed earlier than usual. I will work up to 2g twice daily to reap the full effects for PCOS and maybe more if my anxiety persists.