Re: Medication Combination Fear
Okay, it's important to make a clear distinction between drug "interactions" and "contraindications." Many drugs can create interaction through enhancement or reduction of pharmacological properties or with physiological processes and yet remain safe for patients to use in combination.
In the case of the two drugs mentioned, you need to realize that caution is highly advisable in cases where there is significant renal and hepatic disease, alcoholism and conditions associated with hypoxia (eg. cardiac and pulmonary disease) which could significantly increase the risk of Lactic Acidosis. In fact, the use of Metformin alone in such pre-existing conditions warrants risk of LA.
In all other instances, simple monitoring by your primary care physician is adequate and we are always vigilent about possible interactions and contraindications when considering pharmacological treatment. Many patients can develop phobias about medications in the presence of anxiety because it represents an element beyond their immediate control. In other words, once you've swallowed the pill, it's too late to remain in the corridor of safety that you perceive to be necessary to keep things in control and away from making any sort of self-induced error, ie; swallowing the pills despite certain warnings that are most oftentimes taken largely out of context.
Stay with your prescriptions and if you become concerned, merely contact the prescribing physician. The combination, however, is safe to administer.
You'll be fine.
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Best regards and Good Health