I am currently taking 30mg Mirtazapine along with 10mg Ciprlex. When I started Mirtazapine about 3 months ago it helped for a short time and then the depression started creeping back. A Psychiatrist has now added Cipralex which I am happy to take as I used to take Citalopram (similar drug) and it kept me well for a number of years until last year. I am at my wits end feeling anxiety and low and worry that I am never going to get well again. I am beginning to wonder if Mirtazapine is doing anything for me apart from helping me get off to sleep although I have now started waking through the night. I know tablets will not make all my problems go away (grief), I am doing everything I can to help myself but I'm steadily losing the will to fight this anymore. Is it possible I am on too much medication?