Davevanza
17-08-11, 07:04
Hi,
I've been taking all sorts of antidepressants, antipsychotics, Mood stabilizers, antianxiety medications since 1994.
Back then in 1990's, SSRIs'/ SNRIs were still not in the market.
So my Psychiatrist prescribed me with :
-Imipramine ( just took 10mg twice daily, good for Panic disorder maintenance, but, somehow, i just could not tolerate with its side effects)
- Desipramine ( this is an active metabolite of Imipramine actually, with the advantage, that it causes less sedation and anticholinergic effect. But, I couldn't tolerate it, as it made me feel jittery, agitated, and more anxious.)
- Amitriptyline ( Good for sleep, as i am an insomniac. But again, its side effects stopped me from using it further.)
- Nortriptyline ( actually, an active metabolite of Amitriptyline, with less anticholinergic effect.)
BUT BOTH Desipramine and Nortriptyline acts mainly on Noradrenaline.
So unlike their parent drugs, which affects the 3 Neurotransmitters ( Serotonin (http://www.uncommonforum.com/glossary/serotonin.html), Noradrenaline, Dopamine)
- Moclobemide ( it is a MAOI, but type A, meaning that it prevents the oxidation of the 3 Neurotransmitters, and if it's used within the recommended dose, 600mg or below, no dietary restrictions are required. But, it just didn't work for me, the effect is mild, neither sedating nor stimulating, only a bit of restlesness at the first week. It didn't work for my Anxiety, Panic, and Depression (http://www.uncommonforum.com/glossary/depression.html) problems)
As the SSRIs ( Fluoxetine, Paroxetine, etc), SNRIs ( Venlafaxine, Duloxetine, Milnacipran), and other Antidepressants such as NaSSA ( Mirtazapine, it actually is, 6-aza-Mianserin, an old novel Antidepressants with sedating properties), and others like Atypical Antidepressants/Atypical antipsychotics/Mood stabilisers ( like Neurontin, Pregabalin, Valproate, etc), my Psychiatrist tried me on them , to see which one is suitable for me.
Right now,
I am on :
- Mirtazapine 90mg nocte ( nite)
-Clonazepam 2mg daily
- Tramadol SR occassionally for headache.
The last session i talked to my psychiatrist, I complained about feeling of Lethargy on the next morning after taking Mirtazapine. I also sleep up to 16 hours, during weekend while on it.
So , my Doc, kept in his mind, about the last resort of medication to use.
It is PARNATE ( Tranylcypromine).
My questions are :
1.Has anyone ever taken this?
2. Does it give insomnia (http://www.uncommonforum.com/glossary/insomnia.html)?
3. Is it worth to sacrifice food that I like, while on Parnate?
4. If anyone is on it at the present time, do eating out for Dinner as for socialisation, REALLY INCREASE your blood pressure due to the Tyramine?
Any input is greatly appreciated.
Kind Regards,
David
I've been taking all sorts of antidepressants, antipsychotics, Mood stabilizers, antianxiety medications since 1994.
Back then in 1990's, SSRIs'/ SNRIs were still not in the market.
So my Psychiatrist prescribed me with :
-Imipramine ( just took 10mg twice daily, good for Panic disorder maintenance, but, somehow, i just could not tolerate with its side effects)
- Desipramine ( this is an active metabolite of Imipramine actually, with the advantage, that it causes less sedation and anticholinergic effect. But, I couldn't tolerate it, as it made me feel jittery, agitated, and more anxious.)
- Amitriptyline ( Good for sleep, as i am an insomniac. But again, its side effects stopped me from using it further.)
- Nortriptyline ( actually, an active metabolite of Amitriptyline, with less anticholinergic effect.)
BUT BOTH Desipramine and Nortriptyline acts mainly on Noradrenaline.
So unlike their parent drugs, which affects the 3 Neurotransmitters ( Serotonin (http://www.uncommonforum.com/glossary/serotonin.html), Noradrenaline, Dopamine)
- Moclobemide ( it is a MAOI, but type A, meaning that it prevents the oxidation of the 3 Neurotransmitters, and if it's used within the recommended dose, 600mg or below, no dietary restrictions are required. But, it just didn't work for me, the effect is mild, neither sedating nor stimulating, only a bit of restlesness at the first week. It didn't work for my Anxiety, Panic, and Depression (http://www.uncommonforum.com/glossary/depression.html) problems)
As the SSRIs ( Fluoxetine, Paroxetine, etc), SNRIs ( Venlafaxine, Duloxetine, Milnacipran), and other Antidepressants such as NaSSA ( Mirtazapine, it actually is, 6-aza-Mianserin, an old novel Antidepressants with sedating properties), and others like Atypical Antidepressants/Atypical antipsychotics/Mood stabilisers ( like Neurontin, Pregabalin, Valproate, etc), my Psychiatrist tried me on them , to see which one is suitable for me.
Right now,
I am on :
- Mirtazapine 90mg nocte ( nite)
-Clonazepam 2mg daily
- Tramadol SR occassionally for headache.
The last session i talked to my psychiatrist, I complained about feeling of Lethargy on the next morning after taking Mirtazapine. I also sleep up to 16 hours, during weekend while on it.
So , my Doc, kept in his mind, about the last resort of medication to use.
It is PARNATE ( Tranylcypromine).
My questions are :
1.Has anyone ever taken this?
2. Does it give insomnia (http://www.uncommonforum.com/glossary/insomnia.html)?
3. Is it worth to sacrifice food that I like, while on Parnate?
4. If anyone is on it at the present time, do eating out for Dinner as for socialisation, REALLY INCREASE your blood pressure due to the Tyramine?
Any input is greatly appreciated.
Kind Regards,
David