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15mg Lexapro - but how long until positive or any effects?
Hi,
I have GAD and it's pretty bad at the moment and have had it a few times before in my past. This time, I'm staying on the Lexapro!
I started taking 5mg for 10 days, then 10mg for 10 days and now just started 15mg - and this is where I will stay. My question is, that although I know it takes 4-6 weeks to get full effects, how long have I been on it? Do I count my weeks from when I started the 5mg or when I started the 15mg?
If it's from the 5mg then I've been on it for almost 3 weeks and I can't say I'm reaping ANY benefits yet and infact feel more anxious than when I started, which again I know can happen but I'm so desperate for a little relief. Anxiety is exhausting and debilitating.
I'll try and keep this thread updated too to help others and myself as time goes on...
Thanks all,
Lisa
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
My question is, that although I know it takes 4-6 weeks to get full effects, how long have I been on it? Do I count my weeks from when I started the 5mg or when I started the 15mg?
The clock starts running from when you start taking a therapeutic dose, Lisa. Just how much this is varies from person to person, but the minimum recommended Lexapro (escitalopram) dose is 10mg so you can be sure that will be having a positive affect. Also, while most people do begin to get a response in the 4-7 week range, it can take longer for some, perhaps as long as 12 weeks.
Quote:
infact feel more anxious than when I started
Despite the common myth that serotonin is a 'feel good' neurotransmitter, it is in fact the *opposite hence the spike in anxiety. After a few weeks the brain and body (other organs make/use much more than the brain) will respond to the extra serotonin activity by down-regulating its synthesis and expression and the heightened anxiety and other side-effects will then usually begin to diminish, but they may return for a while after dose increases.
* not strictly true as neurotransmitters don't have any intrinsic qualities, their action is determined by the receptors they bind to, not the molecule itself
I'm curious why you've been prescribed 15mg as the usual initial dose is 10mg, increasing only if that proves insufficient. Have you been on escitalopram before and needed the higher dose?
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Re: 15mg Lexapro - but how long until positive or any effects?
Thank you so much for your helpful and informative response.
I have been on Lexapro before and needed 20mg and stayed on that for 6 months before coming down to 10mg again.
This time my doc said we may have to go to 20mg again. I told my psychologist this and she is the one that suggested I do 15mg instead. I actually wasn’t sure whether to give the 10mg a bit longer but then I also don’t want to waste time if I’m inevitably going to go to 20mg again. I’m hesitant to do 20mg again as I did feel I was a bit emotionless.
Does that all make sense?
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I have been on Lexapro before and needed 20mg and stayed on that for 6 months before coming down to 10mg again.
This time my doc said we may have to go to 20mg again. I told my psychologist this and she is the one that suggested I do 15mg instead.
Unfortunately, you may need the full 20mg given this is the second time you've been on escitalopram because there is *evidence antidepressants (ADs) become progressively less effective each time they are stopped and restarted.
Quote:
I’m hesitant to do 20mg again as I did feel I was a bit emotionless.
If this reoccurs there are a couple of things which may work. Citalopram (Celexa) and escitalopram are nearly the same drug. Citalopram is made up of two isomers, the 'S' form which is the active component, and a 'R' mirror image form which is a poorer fit biologically and so is mostly inactive. Escitalopram is more refined and only contains the 'S' isomer. Despite the chemical closeness there can be differences in side-effects and it possible the emotionless won't be a problem with citalopram, or less so.
The second option is to supplement the 15mg dose with buspirone (Buspar) instead of taking more. Buspirone is generalised anxiety med which only works for some, but in small adjuvant doses it will often increase the effectiveness of SSRIs and also reduce some of their side-effects. It may also reinvigorate SSRIs which have stopped working so might counter the effectiveness loss when returning to an AD mentioned above.
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Re: 15mg Lexapro - but how long until positive or any effects?
Hey - I'm in need of some advice.
I took 10mg for 10 days and 2 weeks of 15mg so 4 weeks all up. Things were really beginning to improve and I could really start feeling the benefits of lexapro. However, since Friday I have taken a crashing nose dive and have probably the worst anxiety I have had to date. I have got really shaky hands, nausea again, loss of apetite and feel extremely anxious its affecting everything.
Does anyone know what's happening to me?! I've recently had the mirena fitted and I am due on now so I guess hormones would play a part but I never get anxiety like this.
I'd be really grateful for some advice. I feel so defeated as I thought things were going upwards.
Thanks,
Lisa
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I took 10mg for 10 days and 2 weeks of 15mg so 4 weeks all up. Things were really beginning to improve and I could really start feeling the benefits of lexapro. However, since Friday I have taken a crashing nose dive and have probably the worst anxiety I have had to date. I have got really shaky hands, nausea again, loss of apetite and feel extremely anxious its affecting everything.
Does anyone know what's happening to me?
It can take up to 12 weeks for antidepressants to fully kick in with most seeing improvement in the 4-7 week range so you're just entering that window, Lisa. Plus, for some there can be periods when progress becomes one step forward, two back, and occasional three, or four back. Welcome to the wacky world of antidepressants! :wacko:
Hormones may also be a factor, though I think it's mostly just the typical initial AD weirdness. The fact this is your second time on escitalopram may also be playing a part.
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I feel so defeated as I thought things were going upwards.
Don't be. What you've experienced is par for the course.
Antidepressants are unlike most medications in that they don't directly address the symptoms, as say, Panadol does where you take a tablet and an hour later the headache is mostly gone. They work on the underlying biological deficits by turbo charging the growth of new brain cells and rewiring connections between neurons and brain regions. It is those new cells and connections which produce the therapeutic response, not the AD. This all takes time and isn't a linear process.
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Re: 15mg Lexapro - but how long until positive or any effects?
Thank you so much PDU,
I was half expecting a blip as I've been here before but I'm a bit thrown this one is lasting so long - the flutterings of anxiety are lasting all day, it's exhausting.
I hope its just the AD weirdness and that it passes soon because it's horrible.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I was half expecting a blip as I've been here before but I'm a bit thrown this one is lasting so long - the flutterings of anxiety are lasting all day, it's exhausting.
Talk to you doctor if it becomes too difficult as the heightened anxiety can be minimised. No one is handing out gold stars for white knuckling anxiety. It's counterproductive.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
panic_down_under
Talk to you doctor if it becomes too difficult as the heightened anxiety can be minimised. No one is handing out gold stars for white knuckling anxiety. It's counterproductive.
I went to the doctor this evening and she recommended going up to 20mg.
I’m a bit fed up as this means side effects again and I really want some relief.
She doesn’t agree with Benzodiazapines and would rather I took propranolol in the interim.
Feeling miffed again.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
She doesn’t agree with Benzodiazapines and would rather I took propranolol in the interim.
I agree with her on the benzodiazepines (BZDs), though probably not for the same reason. The dependency issue is overblown, imho, however, there is strong evidence1 BZDs block the neurogenesis mechanism by which antidepressants work.
Propranolol is a beta-blocker which prevents adrenaline binding to its receptors. This can prevent the adrenaline surge of the flight-or-flight response which can help cope with anxiety, but doesn't directly diminish the anxiety itself. It is definitely worth a try, but if it isn't effective ask for *hydroxyzine instead. It is a mild prescription antihistamine with pretty good anti anxiety properties. Not quite as potent as the BZDs, but often potent enough.
*Hydroxyzine comes in two forms, hydroxyzine pamoate (Vistaril) and hydroxyzine hydrochloride (Atarax). Anecdotally, the pamoate form is claimed to be the more effective anxiolytic, but just how true this is remains a matter of debate in forums.
References:
[1]
Boldrini M, Butt TH, Santiago AN, et al. (2014)
Benzodiazepines and the potential trophic effect of antidepressants on dentate gyrus cells in mood disorders.
Int J Neuropsychopharmacol. Dec;17(12):1923-33 (Abstract | Full text)
Nochi R, Kaneko J, Okada N, et al. (2013)
Diazepam treatment blocks the elevation of hippocampal activity and the accelerated proliferation of hippocampal neural stem cells after focal cerebral ischemia in mice.
J Neurosci Res. Nov;91(11):1429-39 (Abstract)
Sun Y, Evans J, Russell B, et al (2013)
A benzodiazepine impairs the neurogenic and behavioural effects of fluoxetine in a rodent model of chronic stress.
Neuropharmacology. Sep;72:20-8 (Abstract)
Song J, Zhong C, Bonaguidi MA, et al (2012)
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
Nature. Sep 6;489(7414):150-4 (Article | Study full text)
Chen J, Cai F, Cao J, et al. (2009)
Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain.
J Neurosci Res. Oct;87(13):2898-907 (Abstract)
Wu X, Castren E. (2009)
Co-treatment with diazepam prevents the effects of fluoxetine on the proliferation and survival of hippocampal dentate granule cells.
Biol Psychiatry. Jul 1;66(1):5-8 (Abstract)
Stefovska VG, Uckermann O, Czuczwar M, et al (2008)
Sedative and anticonvulsant drugs suppress postnatal neurogenesis
Ann Neurol. 2008 Oct;64(4):434-45 (Abstract)
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Re: 15mg Lexapro - but how long until positive or any effects?
So a quick update, it has been a week on 20mg and its been a rocky road as usual. Headaches, dizzyness, dreamy feeling and of course my old friend increased anxiety. Yesterday I had a really good day but today has been weird again! I also heard on another forum that my clock resets every time I go up a dose and that I can expect another 4-6 weeks of side effects, so that has put a bit of a downer on me again.
The story continues....
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I also heard on another forum that my clock resets every time I go up a dose and that I can expect another 4-6 weeks of side effects,
It would be unusual for the side-effects after a dose increase to continue for 4-6 weeks. Around 10-14 days is more likely. It takes about 7 days for citalopram plasma levels to settle to a steady-state after an increase (or decrease) after which side-effects typically begin the diminish. However, as with everything about ADs, YMMV.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
panic_down_under
It would be unusual for the side-effects after a dose increase to continue for 4-6 weeks. Around 10-14 days is more likely. It takes about 7 days for citalopram plasma levels to settle to a steady-state after an increase (or decrease) after which side-effects typically begin the diminish. However, as with everything about ADs, YMMV.
Thanks again PDU.
I’m on day 12 of the increase and the past few days as well as the feelings of nervousness, I now feel down and have very little motivation to do anything. I feel like I could just lay in bed all day staring out the window (I don’t).
I know I seem impatient but I seem to be getting worse not better. It’s been 5 weeks on 10mg and 4 on 15mg... I have 2 assignments due and prac to attend next week. Any words or advice would be appreciated...
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
Thanks again PDU.
I’m on day 12 of the increase and the past few days as well as the feelings of nervousness, I now feel down and have very little motivation to do anything. I feel like I could just lay in bed all day staring out the window (I don’t).
It is not uncommon for some to feel flat after a dose increase. There is a lot going on in the brain and the affect on other organs can be harsh too. Much of what you're feeling is what happens when we're ill. It's the body's way of dampening activity so there is more energy available to fight off infection, or repair damage.
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I know I seem impatient but I seem to be getting worse not better. It’s been 5 weeks on 10mg and 4 on 15mg... I have 2 assignments due and prac to attend next week. Any words or advice would be appreciated...
They say it is darkest just before the dawn. While this isn't actually true, it is an apt analogy in this case. ADs can, and often do make things worse at the beginning and they tend to hit rock bottom just before the 'magic' starts. So hang in there Lisa. It is not as hopeless as it appears.
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Re: 15mg Lexapro - but how long until positive or any effects?
They say it is darkest just before the dawn. While this isn't actually true, it is an apt analogy in this case. ADs can, and often do make things worse at the beginning and they tend to hit rock bottom just before the 'magic' starts. So hang in there Lisa. It is not as hopeless as it appears.[/QUOTE]
I love this advice and I even took a screen shot!
I’ve been getting progressively worse since starting the 20mg 2 weeks ago. Today could be my final straw. I was in tears on the bathroom floor this morning, had many moments of panic through the day along with racing heart even lying on the bed and shaking. I really don’t think this is doing me any favours. I wonder if I should have given 15mg a bit longer as I had a few good days on this dose.
I’m going to docs on Weds but would be interested in your opinion.
Thanks for everything PDU.
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Re: 15mg Lexapro - but how long until positive or any effects?
Update:
So I went back to the docs after having enough of the racing heart and tremors and we both agreed to go back to 15mg and stay here for at least a month.
The day after I felt a real relief and have been having VERY SLOW improvement but improvement all the same. Now this is what I thought would happen..
I’m certainly not quite out of the woods yet but the light at the end of the tunnel is brighter.
I still have nervousness in the mornings and slight tremor but it’s been 12 days since I went back down to 15mg so possibly still settling in.
Fingers crossed!
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Re: 15mg Lexapro - but how long until positive or any effects?
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Re: 15mg Lexapro - but how long until positive or any effects?
Definitely making improvements every day. I have probably gone from 9 or 10/10 anxiety to a 6/10.
Feeling much more hopeful.
It’s taken such a lot of time, tears and frustration but I think I’ve found the right dose.
Still see my psychologist every couple of weeks which really helps.
Literally taking one day at a time and not looking any further ahead.
Distraction is great. I either go for a walk with the dog, work on an assignment, weed the garden or listen to interesting podcasts.
How are you?
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Re: 15mg Lexapro - but how long until positive or any effects?
Well I'm still going! This is such a rocky road, damn these SSRI's.... Looking back on it, I wish I had stayed on 10mg now... but anyway here I am with my story so far
5mg - 11 days,
10mg - 10 days,
15mg - 19 days,
20mg - 13 days,
15mg - 24 days and counting
It's no wonder I don't know if I'm Arthur or Martha... Still have shaky tremor hands, slight jaw clenching and anxiety STILL high... Urghhh so tired of it....
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
Still have shaky tremor hands, slight jaw clenching and anxiety STILL high... Urghhh so tired of it....
If my abacus is correct, you're now at 9 weeks since first taking 10mg, Lisa, so if the med is going to work then you should begin to notice at least the beginning of an improvement in the next week or two. The jaw clenching may be the last side-effect to go as it and the Lexapro Yawn tend to hang around like unwelcome guests. :sad:
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
panic_down_under
If my abacus is correct, you're now at 9 weeks since first taking 10mg, Lisa, so if the med is going to work then you should begin to notice at least the beginning of an improvement in the next week or two. The jaw clenching may be the last side-effect to go as it and the Lexapro Yawn tend to hang around like unwelcome guests. :sad:
Thanks PDU
Yes timing sounds about right. It’s practically been my whole uni semester - it’s been majorly tough going through this.
Would all the chopping and changing of dose set me back a bit though?
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
Would all the chopping and changing of dose set me back a bit though?
In theory it shouldn't as you didn't drop below the therapeutic dose range, but in practice it can't be ruled out. ADs can be unpredictable because of the way they work. But even in the worst case it shouldn't add more than a couple of days.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
Well I'm still going! This is such a rocky road, damn these SSRI's.... Looking back on it, I wish I had stayed on 10mg now... but anyway here I am with my story so far
5mg - 11 days,
10mg - 10 days,
15mg - 19 days,
20mg - 13 days,
15mg - 24 days and counting
It's no wonder I don't know if I'm Arthur or Martha... Still have shaky tremor hands, slight jaw clenching and anxiety STILL high... Urghhh so tired of it....
Hi Lisa! How are you doing now?
Going up in doses is never fun. I was like you; started at 5 and then slowly made my way up to 15 mg. I've been on 15 mg for over a year now, and it's worked well for me:-).
I think you will start to have positive results soon....
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Re: 15mg Lexapro - but how long until positive or any effects?
Hi!
I just sat down to reply to your thread! Are you still having a blip?
I read it took a while for it to work with you too. It’s so utterly frustrating especially when I hear such success stories!
I have definitely had some good days but it’s still interspersed by crappy ones. I know recovery is not linear but it still always disappoints me so much when I wake up feeling nervous and having the shakes.
Ive lately not really been interested in socialising either as I generally feel like I can’t relax just in case I feel really anxious. I just want to return to being me again and not thinking about it all the time.
Its such a long slog.
I hope you are having a better day xx
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Re: 15mg Lexapro - but how long until positive or any effects?
Yep, I'm still blipping along, although yesterday was a really good day.
Definitely a long slog!
I'm going to order a self help book or two about anxiety, and see if I can pick up some good tips by reading one of those. Have you had any luck with that, or with therapy? I admit I've never done either, as I felt the meds were always enough in the past.
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Re: 15mg Lexapro - but how long until positive or any effects?
I’ve had anxiety on and off for years so I have a bookcase full of self help books!
The most useful has been Paul David - at last a life. Also the happiness trap by Russ Harris. I also watch Dr Amy Johnson on youtube. She is so awesome.
I see a psychologist too who is brilliant but the only thing that can get through it is us!
How long did the meds take for you this time? I think I’m on 10 weeks but 5 weeks on 15mg.. I also have PMS and I always find it worse at that time of the month.
Are your friends understanding? I think mine are confused and wonder why I’m not “ better” yet...
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Re: 15mg Lexapro - but how long until positive or any effects?
I had the very same reaction with Lexepro but my doctor gave me a very low dose of Pregabilin 50mg twice a day and now no more anxiety......
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
Geller
I had the very same reaction with Lexepro but my doctor gave me a very low dose of Pregabilin 50mg twice a day and now no more anxiety......
It took a long time or the side effects?
Do you take the Pregabalin alongside the Lexapro or instead of?
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Re: 15mg Lexapro - but how long until positive or any effects?
I’m not sure when to call it a day with this led now. I’m about to go into a lecture and feeling anxious... this has certainly not helped me in the way I hoped it would. The side effects of agitation are lingering on...
or is 15 too much? So over it.
I’m functioning but it’s not easy.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I’m not sure when to call it a day with this led now.
If I've done the calculation right you've now been on 15mg for 30 days which is still a little early to draw a firm conclusion, imho. I'd give it at least another 2 weeks.
Quote:
The side effects of agitation are lingering on...
or is 15 too much?
Given you've needed to take 20mg in the past I don't think you're on an excess dose now. Agitation tends to occur a little more often with escitalopram than the parent compound citalopram, so if it continues to be a problem switching to the older med might resolve it. As they share the same active drug (citalopram also contains a mostly inactive isomer of it) there should be few if any side-effects.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
panic_down_under
If I've done the calculation right you've now been on 15mg for 30 days which is still a little early to draw a firm conclusion, imho. I'd give it at least another 2 weeks.
It’s been 5 weeks on 15mg. 12 wks since I started 10mg..
Given you've needed to take 20mg in the past I don't think you're on an excess dose now. Agitation tends to occur a little more often with escitalopram than the parent compound citalopram, so if it continues to be a problem switching to the older med might resolve it. As they share the same active drug (citalopram also contains a mostly inactive isomer of it) there should be few if any side-effects.
I did take 20mg a couple of years ago but I was in a much more debilitating state than I am this time.
If I were to switch to Citalopram, is it a straight switch or do I have to come off ESC than back on Cit?
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
If I were to switch to Citalopram, is it a straight switch or do I have to come off ESC than back on Cit?
A straight overnight switch should present few, if any problems. The active drug in both is exactly the same, the S-enantiomer of citalopram, aka escitalopram, the difference is citalopram also contains a mostly inactive form of the drug, the R-enantiomer, which produces some minor differences in how the drug interacts with biology, but most won't notice any difference except maybe in side-effects. There can be subtle differences which is actually what you'd be hoping for with respect to the agitation. I can't guarantee it'll work, but there is usually little downside in giving it a shot. It is just as easy to switch back if you choose to.
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Re: 15mg Lexapro - but how long until positive or any effects?
Hey PDU,
Before you referred to the amount of time I'd been on 10mg but now you mention the 15mg. FWIW, it's now been 13 weeks since I started the 10mg and almost 6 weeks on the 15mg.
I probably had one of my worst days yesterday and was back to the diazepam and propanolol. Today I feel a bit spaced out and down in the dumps (fed up).. I'm so disappointed. I am seeing my GP on Tuesday and see what he thinks.
Part of me wants to keep going, part of me wants to come off and reset and start again and part of me wants to go to 10mg ... I hate how there is no quick fix to this.
thanks for your support this far though.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
FWIW, it's now been 13 weeks since I started the 10mg and almost 6 weeks on the 15mg.
If the 15mg is going to work then from now on would be when it is most likely too. That said, I suspect it'll take 20mg.
Quote:
Part of me wants to keep going, part of me wants to come off and reset and start again and part of me wants to go to 10mg
There are good arguments for the first two, but I doubt 10mg will work, Lisa.
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Re: 15mg Lexapro - but how long until positive or any effects?
I saw a new GP yesterday who said he didn’t think meds would work for me at all which was not the best thing to hear! He’s doing full blood work up and then go from there. He thinks I need to work more on my psychology, which I have been actively doing for years.
After waking at 4am today with a major panic, I think I’ve made me own decision to come off. I’ve given it a damn good go.
I’ll prob go down to 10mg for a while and take it slow from there.
He mentioned Valdoxan but I’m keen to try Pristiq..
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
LisaS
I saw a new GP yesterday who said he didn’t think meds would work for me at all
Based on what? Escitalopram worked for you in the past so obviously you can and do respond to ADs. The fact it hasn't this time can probably be attributed to the loss of efficacy after discontinuation and restart hoodoo, but this doesn't mean no ADs will work and this would be true even if SSRIs were the only ADs available, which isn't the case. There are many other ADs acting on a range of different pathways.
BTW-have you been treated by a psychiatrist in the past? If not, now might be a good time to ask for a referral.
Quote:
He’s doing full blood work up and then go from there. He thinks I need to work more on my psychology, which I have been actively doing for years.
Blood work is always a good idea as there are some conditions which can produce similar symptoms as the anxiety disorders, though they are uncommon. As for therapy, it too could be worth while doing a formal refresher.
Quote:
After waking at 4am today with a major panic, I think I’ve made me own decision to come off. I’ve given it a damn good go.
I’ll prob go down to 10mg for a while and take it slow from there.
I'd be tempted to ask for a small dose of buspirone (Buspar) to be added. It is a GAD specific med which works very well for a few and not at all for most and then only for GAD and maybe social anxiety. However, it has a pretty good track record for increasing the effectiveness of SSRIs and SNRIs and/or reinvigorating those that are/have failed. It may also ease some of the common SSRI/SNRI side-effects. If it is going to work you can expect to see positive indications within 2-3 weeks, though it may take another few to hit peak efficiency.
Quote:
He mentioned Valdoxan
Valdoxan (agomelatine) is a unique melatonin acting AD which doesn't seem to be prescribed much, possibly because it wasn't able to gain FDA approval due to indifferent trial results and some doubts about its affect on the liver. It took several attempts before the TGA approved it in AU too (PDF). It might prove to be a very effective med for you, but it is well down my to try list. It does reportedly usually produce few initial side-effects and appears to be easy to discontinue.
Quote:
but I’m keen to try Pristiq..
Any reason?
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Re: 15mg Lexapro - but how long until positive or any effects?
Hi PDU
I appreciate your response and totally agree with you regards to the efficacy of SSRIS and me. I have had success with Effexor and Escitalopram in the past so I’m not immune.
I have seen a psychiatrist last year when I was having excessive twitching from Sertraline and my plan was to come off and restart Pristiq. But when I came off I felt great so didn’t restart anything which has led to anxiety creeping back again.
Pristiq came up as a recommendation from a DNA test I did due to the fact it is independent of pharmacogenetic status, apparently.. plus being an offshoot of Effexor that has worked for me in the past.
I will try and see the psych again but I’m aware there is a long wait list....
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Re: 15mg Lexapro - but how long until positive or any effects?
I am on Valdoxan,along with Lyrica.Thinking about asking my psychiatrist about changing the Valdoxan it is so expensive.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
Quinn1
I am on Valdoxan,along with Lyrica.Thinking about asking my psychiatrist about changing the Valdoxan it is so expensive.
How many kidneys do you have to sell each month?
If it was working well then it might be worth the price, but that you're also taking Lyrica (pregabalin) suggests it isn't.
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Re: 15mg Lexapro - but how long until positive or any effects?
Quote:
Originally Posted by
panic_down_under
How many kidneys do you have to sell each month?
If it was working well then it might be worth the price, but that you're also taking Lyrica (pregabalin) suggests it isn't.
The GP prescribed Lyrica for nerve pain 3yrs ago,my psych put me on Valdoxan 6mths ago and I have been ok on them,
I take a few more meds for HIV,so far so good as in no interactions.
I already sell a lot of kidneys on the black market.:D