Re: Venlafaxine & serotonin toxicity
Mixing ADs can cause serotonin sydrome, but cases are rare apparently.
I'm starting duloxetine (a SNRI like venlafaxine) tomorrow alongside mirtazapine. 2 low doses, it's worth the slight risk for the pay off.
From studying ADs myself (as I've tried many) I find that the scare stories seem to come from American sites, where GPs are no doubt more used to being sued and therefore the whole medicine culture is naturally more cautious.
I read from some NHS prescribing guidance that mirtazapine plays nice with other ADs because it's in a pharmacological class of it's own (not an SSRI, SNRI etc).
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Daily Medication for GAD: Mirtazapine 15mg