I've been solely on 60mg of Duloxetine for 7 days now and apart from a little queasiness, feeling cold and difficulty sleeping(all minor except the sleeping), I don't feel anything, it's almost as if I'm not taking anything and the last 2 or 3 days I've felt so down. In the past I've thought of suicide although I'd never do it, I have thought about and I am again. I have no motivation, I literally can't be bothered with anything. My dad used to say I have to push myself, and I am, everyday. I have cats and if it wasn't for them I'd stay in bed all day. I have no family(the last of my relatives died October 2009 and my dad August 2009), no friends(thanks to a controlling ex and a lack of confidence). My son lives with me, but he's 21 and goes to uni, he has his own life and we don't do much together now he's older.
Finally the reason for my post is to ask, is it usual for a medication such as this to worsen depression in the early days of taking it? I know it can make anxiety worse.
Sorry if my post is untidy, I have an untidy mind at the moment.

Lynn