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Thread: Not working any more?

  1. #1
    Join Date
    Dec 2012
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    Unhappy Not working any more?

    Hello all I've been on Duloxetine for about 2 months and it feels like its stopped working, is that possible after such a short time?

    I've felt pretty rough for the last few weeks actually, but lately (a few days) I feel myself getting lower and lower everyday. I'm back to thinking about suicide or hurting myself. I had a dr's appointment Monday just gone, and all he did was repeat my prescription and told me there is no higher dose than 60mgs for depression. So this is it? It stops working then I come off, then I try something else? I'm confused and fed up with all this, so if anyone can help me I'd be really grateful. Thank you.

    Lynn.

  2. #2
    Join Date
    Jun 2013
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    2,026

    Re: Not working any more?

    Lynn, hi, I'm not an expert and I'm new here, but I didn't want your post to go unanswered for long. Your doctor ought to be taking it really seriously if you are reporting suicidal feelings, is there anybody else in the practice you can talk to? Do you have people around - anybody - you can tell how you are feeling? Can you maybe talk to someone at the Samaritans or SANE so that you can get some help to hang in there?
    Remember, the doctor is not an expert on YOU. This sounds horrible, please ring and ask if there is someone you can see, or someone at the hospital if you are under someone there (or ask for a referral?)
    Keep posting here and keep browsing the forums, anything to keep yourself occupied til others come and answer.
    Gill
    Last edited by Speranza; 27-06-13 at 16:52. Reason: Spelling
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    All manner of thing shall be well... (Julian of Norwich)

  3. #3
    Join Date
    Dec 2012
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    57

    Re: Not working any more?

    Hello Gill, thanks very much for your reply.
    I didn't actually tell the dr about my thoughts, partly because they're intermittent and partly because I'm a bit scared about what would happen after, stupid I know.
    I've been thinking and I'm going to ask to see another dr at the practise, get his/her opinion on things and maybe even ask to be referred because I've never been told that I would be if things didn't improve.
    I don't think my dr would even prescribe something else along side the Duloxetine, but maybe another one would, we'll see.
    Thanks again for replying.
    Lynn

  4. #4
    Join Date
    Mar 2013
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    Re: Not working any more?

    Hi Willow,

    I think it would be a good idea to go back and speak to one of the doctors, let him know how you feel. Also, ask to be referred for some sort of counselling, as antidepressants alone are not the answer and counselling would help.

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  5. #5
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    Re: Not working any more?

    Hi Lynn

    I've been on duloxetine for 2½ months now, and there are days I feel it's not working, till I remember how I was before.

    You can go higher on the drug (90 and 120mg) but those dosages are rare and from what I read, of you don't respond to 60, there's no point going higher.

    Certainly the last time I saw my GP (a few days ago) he refused to entertain the idea of a dosage increase.

    As for drug benefits wearing off, I was on pregabalin for 4 months and that certainly did tail off after 2 months, until after 4 it was doing very little, if anything for me.

    All the best

    Mark
    __________________
    Daily Medication for GAD: Mirtazapine 15mg

  6. #6
    Join Date
    Dec 2012
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    Re: Not working any more?

    Thanks all for your responses.

    I've decided to give it another month and if i dont feel any better, then I'll see about another change. At the moment though I've got another problem, I took my prescription to the chemist on Thursday only to be told no Duloxetine in stock, the pharmacist was going to try to get some from another chemist, but to no avail. Just come back from the chemist again, and still no Duloxetine I've only got 1 tablet left, and I'm now slowly starting to panic that I'm going to run out. I won't know if I can have my latest supply till tomorrow afternoon.

    Has anybody else been left with no medication, and how did you cope with the symptoms of withdrawal?

    Lynn.

  7. #7
    Join Date
    Dec 2012
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    Re: Not working any more?

    Even if you miss a day you should be OK. I missed a dose one (I think I ended up taking it 8 or 9 hours late) but felt no ill effects.

    Hope you got your supply now.

    The Boots I pass on my walk home from work is terrible for having stocks of anything. The last few times I've been I've had to leave my prescriptions with them and go back the next day.
    __________________
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  8. #8
    Join Date
    Nov 2010
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    2,934

    Re: Not working any more?

    Low stocks of a medication at a pharmacy have happened to me both in Australia and Japan, but never no stocks of a commonly prescribed medication like duloxetine.

    Is there not some law in the UK that requires pharmacies to hold reasonable stocks of medications? If so, you could lodge a complaint, which might have some effect.

    In Australia, pharmacies can dispense emergency supplies of a medication without prescription, provided that they have authorization over the phone from a doctor or another pharmacist holding an unfilled prescription.

  9. #9
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    Re: Not working any more?

    Did you see the doctor?
    __________________
    All manner of thing shall be well... (Julian of Norwich)

  10. #10
    Join Date
    Dec 2012
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    57

    Re: Not working any more?

    Hi sorry its taken me so long to reply. Computer troubles!

    Well to cut a long story short, I finally got my Duloxetine after about week, was getting pretty concerned there for a while. No more improvement in me this past month, the only difference is that my anxiety has increased especially in the mornings, the churning stomach is back. Mood is still low, as is motivation, enjoyment etc.

    Had a doctors appointment yesterday, explained all that and he said to try a different med, Edronax (Reboxetine)? Has any of you heard of it, or tried it? Any good?

    I also mentioned to him that I was thinking about trying CBT, he gave me a phone number to ring for something called I something, it had 4 letters??

    Also the doctor said I've tried nearly all the different types of these meds and he seems bored with me now. He said if these new ones aren't any good then he doesn't know what to suggest.

    Thanks for reading.

    Lynn

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