Finally saw my psychiatrist today and she's put me on Cymbalta as it appears Cipralex has pooped out on me after 2 1/2 years. I'm to take 30mg Cymbalta with 10mg Cipralex for a week and then 60mg Cymbalta with 10mg Cipralex until I see her next. Cipralex was my first AD and it was not fun starting on it. I assume it won't be so bad switching since I'm on something but what can I expect? Anyone done this switch?