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Thread: A timetable for recovery on Fluoxetine / prozac

  1. #571

    Re: A timetable for recovery on Fluoxetine / prozac

    Well not feeling great today. Woke up with thoughts of being forever stuck feeling like this. Then tell myself it’s gonna improve and hang in there. It’s really hot down under which doesn’t help the perspiration! We have also been getting the ash from Austalia’s Fires, along with their heat. Would like a good excuse to snuggle up in a duvet & watch tv all day! But will push myself to get out again today.

  2. #572
    Join Date
    Dec 2019
    Posts
    50

    Re: A timetable for recovery on Fluoxetine / prozac

    Quote Originally Posted by Summerdaze View Post
    Would like a good excuse to snuggle up in a duvet & watch tv all day! But will push myself to get out again today.
    So do both. As a "reward" for forcing yourself to go outside and do something, when you come home, take a relaxing shower/bath, hit the couch/bed and watch some flix.
    Be sure to eat also and stay hydrated...

  3. #573

    Re: A timetable for recovery on Fluoxetine / prozac

    Just an update. Started week 5 of 40 mgs yesterday & have felt terrible for 3 days. Taken 1/2 lorazepam 2 out of 3 days to try & keep the panic attacks under control. I知 willing myself to hang on. Hopefully about to turn the corner. I was having the odd beer with dinner but I think I値l give that away for the time being. Don稚 know if it was helping matters!

  4. #574
    Join Date
    Jan 2017
    Posts
    1,984

    Re: A timetable for recovery on Fluoxetine / prozac

    Quote Originally Posted by Summerdaze View Post
    I was having the odd beer with dinner but I think I値l give that away for the time being. Don稚 know if it was helping matters!
    Probably not.

    Anxiety and depression are the symptoms of atrophy of parts of the hippocampal regions of the brain caused by high brain stress hormone levels, particularly of cortisol, killing brain cells and inhibiting the growth of replacements (neurogenesis). ADs work by stimulating the growth of new cells. It is the new neurons and the interconnections they form which produce the therapeutic response, not the meds directly. For a more detailed explanations see: Depression and the Birth and Death of Brain Cells (PDF) and How antidepressant drugs act.

    The problem is alcohol is a CNS depressant which has the same affect on hippocampal neurogenesis as cortisol. Even relatively moderate drinking can reduce hippocampus neurogenesis by nearly half (see also: Morris SA, 2010; Crews FT, 2003).

    The other thing to be aware of is that the AD+alcohol combo can produce unpredictable results. Some days you may be able to drink a herd of alcoholic elephants under the table without raising a sweat, on another half a pint might turn legs to rubber. Alcohol may also increase fluoxetine side-effects.
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  5. #575

    Re: A timetable for recovery on Fluoxetine / prozac

    Quote Originally Posted by panic_down_under View Post
    Probably not.

    Anxiety and depression are the symptoms of atrophy of parts of the hippocampal regions of the brain caused by high brain stress hormone levels, particularly of cortisol, killing brain cells and inhibiting the growth of replacements (neurogenesis). ADs work by stimulating the growth of new cells. It is the new neurons and the interconnections they form which produce the therapeutic response, not the meds directly. For a more detailed explanations see: Depression and the Birth and Death of Brain Cells (PDF) and How antidepressant drugs act.

    The problem is alcohol is a CNS depressant which has the same affect on hippocampal neurogenesis as cortisol. Even relatively moderate drinking can reduce hippocampus neurogenesis by nearly half (see also: Morris SA, 2010; Crews FT, 2003).

    The other thing to be aware of is that the AD+alcohol combo can produce unpredictable results. Some days you may be able to drink a herd of alcoholic elephants under the table without raising a sweat, on another half a pint might turn legs to rubber. Alcohol may also increase fluoxetine side-effects.
    Thanks PDU, makes perfect sense. I have woken up ok this morning (no alcohol last night) Will go & do a yoga class while the weather is abit cooler.

  6. #576
    Join Date
    Feb 2020
    Posts
    10

    Re: A timetable for recovery on Fluoxetine / prozac

    Hello everyone, I have been taking paxil 20mg for 6 years.
    I arrived at 2mg then I did not manage to go down lower; so I made a prozac direct switch;
    when I did I had balance losses and today I enter in my 5 weeks and I am still not stable. I still have balance losses and anxiety.
    I wonder if the dose of 2mg is sufficient .
    Thanks

  7. #577
    Join Date
    Jan 2017
    Posts
    1,984

    Re: A timetable for recovery on Fluoxetine / prozac

    Quote Originally Posted by velia View Post
    Hello everyone,
    to NMP, velia,

    I have been taking paxil 20mg for 6 years.
    I arrived at 2mg then I did not manage to go down lower; so I made a prozac direct switch;
    when I did I had balance losses and today I enter in my 5 weeks and I am still not stable. I still have balance losses and anxiety.
    I wonder if the dose of 2mg is sufficient .
    So you switched from 2mg paroxetine (Paxil) to 2mg fluoxetine (Prozac) to make it easier to wean off antidepressants? If so, the switch should ideally have been done at 20mg. The problem is that at very low doses the impact of the drug is minimal, compounded by the very long fluoxetine half-life which means it takes a long time for blood plasma levels to stabilize - up to 30 days for fluoxetine itself and up to 80 days for its active metabolite norfluoxetine, which generates most of the therapeutic response. I think you need to discuss this with your doctor, but I don't see the point of continuing to take fluoxetine at such a low dose. Taking 5mg may ease the withdrawal effects, but whether it will make quitting easier in the long run is debatable, imho.

    BTW-how are you taking the fluoxetine, in liquid form?
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  8. #578
    Join Date
    Feb 2020
    Posts
    10

    Re: A timetable for recovery on Fluoxetine / prozac

    Hi
    thank you for your answer, I take prozac 20mg for 5ml . unfortunately, I don't trust my doctor.you think the 2mg are not enough .I took it precisely because I could not wean the paxil. I don't understand very well when you say "but I don't see the point of continuing to take fluoxetine at such a low dose. Taking 5mg may ease the withdrawal effects, which is the goal whether it will make quitting easier in the long run is debatable" sorry I'm French

  9. #579

    Re: A timetable for recovery on Fluoxetine / prozac

    Hi everyone. I see there are some recent posts and therefore there are still some people accessing this page!? I知 4 weeks back on Prozac and been really struggling. This forum has been very useful and I will stick it out. I知 keen to chat to people at a similar point as I am. Also there is someone with a username called peachy. Do they still see this forum? X

  10. #580

    Re: A timetable for recovery on Fluoxetine / prozac

    Your post is encouraging

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