Definately first thing in the morning. It takes me ages to get anything done. Going through the worst of my depression as well, I used to cry as soon as I woke up.Once I,m up and about and start doing things I find things a lot easier. I think the key is to get up, don't dwell and keep busy I am writing this at 7:15 am so now I,m gonna log off, go have a shower, get dressed and hopefully soon I,m ready to face the day. LOL