Hi I am currently taking Sertraline and have been for 5 months for GAD, I have to say it is making me worse. Although it did work for my previous bout in 2011 and I had been fine till I stopped taking it I have been reading all the threads on here and am thinking of giving venlafaxine a go, I've got an appointment with psychiatrist on Monday. Firstly has anyone gone from Sertraline to venlafaxine with success without tapering Sertraline, I'm a lucky one who has never suffered withdrawal symptoms from AD's? Has it worked? I know every one is different but what side effects did you get at first? How long before you noticed a difference? Sorry for the long thread xx