When I first went on fluox I had terrible side effects but I'm not sure if it was me or the tablets, if that makes sense. I was so bad my husband called an ambulance but after heart checks etc they said I was fine. Since then I have never got in that state so I don't know if it was my head or not. Maybe they do make a difference but not what I was expecting. I never want to change dosage or change meds, can't go thro that again. Mornings are horrible, I try to divert my thought but it's very hard. By evening I have calmed down