Re: Allergies to antidepressants
Originally Posted by
Limb
I am new on this site.
to NMP,
Have had allergies and bad reactions to all antidepressants. I need an antidepressant, but doctors say I am allergic to all kmown classes, what to do?
"Bad reactions"/side-effects I believe, allergies, not so much. Antidepressants (ADs) range from primarily serotonin reuptake inhibitors through combination serotonin+noradrenaline, aka norepinephrine, inhibitors to primarily noradrenaline reuptake inhibitors in 4 main classes, SSRIs, SNRIs, TCAs and MAOIs, plus several in classes of their own that have little, if any affect on either serotonin, or noradrenaline pathways, and with a wide diversity of chemistry even between ADs in the same group. It is very, very unlikely that all of them would trigger a true allergic reaction, especially given some of them are very potent antihistamines, indeed more potent than many of the meds marketed as antihistamines.
OTOH, side-effects at the beginning are fairly common, especially with SSRIs and SNRIs because serotonin has many functions throughout the body which may be affected as much, or even more than the brain by the meds initially. They can't always be avoided, but they can usually be kept at tolerable levels.
What have you tried, what was the maximum dose taken, how long did you take that dose and what caused you to stop taking it?
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.