Hello, has anyone been on either of these 2 meds and found it effective for social anxiety/fear and the likes? Has it made you more calm and peaceful inside and reduced stress? thanks for any comments. I have severe social anxiety and wondering if these two would be effective.
according to this study clomipramine is stronger than imipramine for anxiety disorders: ncbi.nlm.nih.gov/pubmed/1527228
I believe that is becuase clomipramine reduces CRH (stress signal: Corticotropin-Releasing Hormone) mRNA up to 74% vs Imipramine which only reduces CRH by 37% (still a lot). any thoughts on this?
clomipramine ncbi.nlm.nih.gov/pubmed/15214866
imipramine ncbi.nlm.nih.gov/pubmed/1671867
max dose of clomipramine is 250mg/day
and max dose of imipramine is 300mg/day
also this is way I think clomipramine is so effective for OCD cause it reduces CRH massivly.
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