Hi guys,

I've been on Pregabalin for GAD for the last four years, gradually increasing it up to 300mg which worked well for a couple of years. I felt anxiety creeping back in over Christmas (a mini relapse) and so upped the dose to 400mg as agreed with the psychiatrist. This helped to level things out until last week where it just seems to have stopped working. I probably am still feeling some of it's affects but it almost feels like I've gone back to square one which is pretty terrifying!

My question is can a medication start to work again, can it just have a period of ineffectiveness or is it a question of when it stops working than that's it? I'm unsure of whether to ask to go up to 600mg which is the maximum dose for anxiety or whether I need to accept that it's no longer working for me and to try something else? Thank you