Sorry, me again. Does anyone know if it's normal to have increased agitation with quetiapine when increasing the dose? I've not had this level of climbing the walls for a couple of weeks, I guess when I last increased. 2 days now on 150mg, might up to 200mg tonight or tomorrow. Tried everything I can think of: diazepam, brisk walk, distraction, music. Psych wants me to read a book but concentration has gone out of the window. The therapist said to call Samaritans for these times, but I don't particularly want to talk about it, I just want to be anaesthetised. Is this the drug? The depression? Tried to tell a relative but she didn't understand it's not panic. It's being unable to sit still, literally tearing your hair out, and feels like you can't stand to be in your own skin. If it's the quetiapine increase I can hopefully get through it. Pulisa, does this sound like what you get? Can I ask what you find helpful? Sorry for rambling. I don't know what else to do.