Re: Starting quetiapine
Originally Posted by
Jo79
i’m now thinking I should ask my psychiatrist if I can change one of my drugs to a TCA, probably the mirtazapine and keep taking the venlafaxine and quetiapine for now. Is that a do-able combination?
Depends on the TCA as, unlike the SSRIs, they don't all do the same thing. The serotonergic biased TCAs, i.e. amitriptyline, imipramine and especially clomipramine would conflict with venlafaxine, but the noradrenergic TCAs, desipramine, nortriptyline and lofepramine could work.
I’m reluctant to change the ven as I know it can be rough to get off.
Perhaps, but taking a med that isn't working because it could, repeat could, it is not a certainty, be difficult to discontinue is unwise, imho, especially if it prevents getting on a med that could be the answer for you. Quitting venlafaxine directly can be problematic. Switching to the long half-life fluoxetine and weaning off it is usually easier.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.