Results 1 to 4 of 4

Thread: Buspirone as an addition to SSRIs

  1. #1
    Join Date
    Sep 2019
    Posts
    208

    Buspirone as an addition to SSRIs

    How well does buspirone work as an addition to SSRIs for anxiety? And why doesn’t it work so well if you have been using benzodiazepines beforehand? Thanks

  2. #2
    Join Date
    Jan 2017
    Posts
    1,787

    Re: Buspirone as an addition to SSRIs

    Quote Originally Posted by Windywel View Post
    How well does buspirone work as an addition to SSRIs for anxiety?
    Buspirone has a pretty good track record for boosting the effectiveness of SSRIs/SNRIs/serotonergic TCAs, reinvigorating those which have pooped out and for moderating some of their side-effects, particularly sexual dysfunction.

    And why doesn’t it work so well if you have been using benzodiazepines beforehand?
    This is supposedly the case when taken alone for GAD possibly due to an interaction between the tryptamine system mediated by buspirone and BZD systems. However, I assume buspirone wasn't prescribed for its direct anxiolytic properties, but to enhance the effectiveness of citalopram and maybe speed up it's kick-in. But it may take some weeks for buspirone to work so...
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  3. #3
    Join Date
    Sep 2019
    Posts
    208

    Re: Buspirone as an addition to SSRIs

    Thanks PDU - so it doesn’t really work that well on anxiety? Does it have side effects when you first start taking it?

  4. #4
    Join Date
    Jan 2017
    Posts
    1,787

    Re: Buspirone as an addition to SSRIs

    Quote Originally Posted by Windywel View Post
    so it doesn’t really work that well on anxiety?
    Buspirone works very well for some and not at all for many, and then only for GAD and maybe social anxiety. But as per my earlier post, I don't think it was prescribed to directly affect your anxiety levels, but to boost citalopram.

    Does it have side effects when you first start taking it?
    Usually only mild ones. Otoh, it could ease some SSRI side-effects.
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Similar Threads

  1. Buspirone as an addition to an SSRI
    By Windywel in forum General Anxiety / Generalised anxiety disorder (GAD)
    Replies: 2
    Last Post: 10-11-19, 07:40
  2. Buspirone & SSRIs
    By USER12 in forum Buspirone / Buspar
    Replies: 3
    Last Post: 04-01-18, 20:03

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •