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Thread: Changing meds

  1. #1

    Changing meds

    Hi Iíve been a member of this forum for years but donít post much but do browse a lot. Iím having a really bad time at the moment with panic/low mood. Iíve been on my current meds (lofepramine)/for years and I really donít think itís working any more. Iíve spoken to my GP about this but she tells me that Iíll need to come off one before going onto another. Iím so fragile at the moment that I donít think I can put myself through this in case they are holding me together. Iím also scared of what Iíll go on - Iíve heard a lot of good things about sertraline or citalopram but I did try an SSRI (fluoxetine) many years ago and this made my anxiety a lot worse. All this really freaks me out and seems to make recovery impossible. Iím experimenting with CBD oil but havenít had much luck as yet but itís early days. Any advice would be appreciated. Thanks.

  2. #2
    Join Date
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    Re: Changing meds

    Quote Originally Posted by Candy6 View Post
    Iím having a really bad time at the moment with panic/low mood. Iíve been on my current meds (lofepramine)/for years and I really donít think itís working any more.
    How much are you taking?

    Iíve spoken to my GP about this but she tells me that Iíll need to come off one before going onto another.
    Doing a washout before starting another AD is only necessary when switching to/from a MAOI class AD. For all other ADs cross tapering is the better option, although most can handle an overnight switch from one SSRI to another.

    Iím so fragile at the moment that I donít think I can put myself through this in case they are holding me together. Iím also scared of what Iíll go on - Iíve heard a lot of good things about sertraline or citalopram but I did try an SSRI (fluoxetine) many years ago and this made my anxiety a lot worse.
    I suggest switching to imipramine via a cross-taper before trying a SSRI. Imipramine (Tofranil) was the 'gold standard' AD for panic disorder for many decades until the SSRIs and SNRIs became available. It wasn't replaced by SSRIs because they were more effective, but because they are safer in overdose, although it turns out this isn't true of all of them.
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