Re: Started Valdoxan/Agomelatine today, feeling scared
Originally Posted by
BrokenGirl
My GP said that after 2 weeks I should definitely see an improvement with Pregabalin if they are to work for me. I saw a slight improvement, so maybe my dose should have been increased rather than giving up on them.
The dose was probably inadequate with doses of between 400-600mg more usual for anxiety.
She also said that SSRIs and SNRIs take many weeks to kick in but that Pregabalin and Agomelatime are much faster to work.
She's probably right on pregabalin, but optimistic for agomelatine. It works by the same mechanism as other ADs and will probably take just as long as them to kick-in, typically 5-12 weeks.
If the Agomelatine isn't working for me at that stage I think I might ask her about going back on Pregabaline but on a higher dose.
Pregabalin is not a good long-term anxiety med, imo. It is becoming increasing obvious that it has the same dependency issues as the benzodiazepines.
I can't take SSRIs or SNRIs due to the side effects, mainly severe migraines, so I'm kind of limited with what I can take.
SSRIs/SNRIs are not the only ADs, or arguable even the most effective. A tricyclic class antidepressant (TCA) may provide the relief you desire without the migraines.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.