I have tried many antidepressants for anxiety disorders including TcA’s, Maoi’s, Ssri’s, Snri’s. The only combination
that worked for a few years was moclobemide and pregabalin. I have tried reinstating these at different doses over
the last four years with no success.
I could not get upto therapeutic doses especially on clomipramine and imipramine unfortunately.
pdoc has give me this as a last option, starting at 25mg and working up to 75mg over time.

Is this a good medication for depression/ anxiety, I see it’s used a lot for insomnia/ hives and has a high affinity for
histamine. I’m guessing that’s where the anxiety relief may come from similiar to mirtazapine.

Any experiences with this med anyone and PDU I would appreciate your opinion?

Thanks
Mark