Results 1 to 6 of 6

Thread: 40mg Fluoxetine not working yet

  1. #1
    Join Date
    Mar 2019
    Posts
    165

    40mg Fluoxetine not working yet

    Hi all,
    I changed over to Fluoxetine from venlafaxine 8 weeks ago now. I did 3 weeks on 20mg, 2 weeks on 30mg and then 3 weeks ago I increased to 40mg and reduced my mirtazapine from 45 to 30mg.

    I’m feeling pretty rubbish, OCD has increased and my mood is very low. I’ve read that this is a slow drug so do I just give it more time? I’ve done 8 weeks in total but do I need to wait 8 weeks at my current dose before I see a difference?

  2. #2
    Join Date
    Apr 2003
    Location
    , , United Kingdom.
    Posts
    46,966

    Re: 40mg Fluoxetine not working yet

    I was told to give Prozac 6 months to get full effect.
    __________________
    Nicola

    “Don't be afraid of death; be afraid of an unlived life. You don't have to live forever, you just have to live.” - Natalie Babbitt

    Please help keep NMP running and donate to the running costs: http://www.nomorepanic.co.uk/donate




  3. #3
    Join Date
    Jan 2017
    Posts
    3,555

    Re: 40mg Fluoxetine not working yet

    Quote Originally Posted by Jo79 View Post
    I’m feeling pretty rubbish, OCD has increased and my mood is very low. I’ve read that this is a slow drug so do I just give it more time? I’ve done 8 weeks in total but do I need to wait 8 weeks at my current dose before I see a difference?
    The long fluoxetine half-life has several positives, but the downside is you can age appreciably waiting for it to kick-in. It takes about a month just for fluoxetine plasma levels to stabilise after a dose increase (or decrease). I can't say how long you may still need to wait as that comes down to individual biology, but my guess is another 3-4 weeks is likely and as Nicola has said, the full effect can take much longer. Sorry

    I suggest you talk to your GP about how you're feeling as he/she may be able to help you with the low mood and OCD. Stoic suffering is counterproductive.
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  4. #4
    Join Date
    Mar 2019
    Posts
    165

    Re: 40mg Fluoxetine not working yet

    Thanks guys, so looks like I need to try and be a little bit more patient with myself. 4 weeks on 40mg now and still feeling incredibly anxious with lots of intrusive thoughts. I feel completely disconnected from my family and I feel completely intolerant of my in laws. Looked at the side effects list and feeling hostile is listed there so I guess that’s why.

    I noticed that I posted this on the venlafaxine thread but meant to put it on the fluoxetine one. Is there anyway it can be moved?

  5. #5
    Join Date
    Mar 2019
    Posts
    165

    Re: 40mg Fluoxetine not working yet

    Still got loads of anxiety/OCD, nearly 6 weeks on 40mg now and I am just wondering if it is possible I could still be feeling some withdrawal effects from coming of the ven and lowering the mirtazapine? I stopped ven completely 11 weeks ago.

  6. #6
    Join Date
    Jan 2017
    Posts
    3,555

    Re: 40mg Fluoxetine not working yet

    Quote Originally Posted by Jo79 View Post
    Still got loads of anxiety/OCD, nearly 6 weeks on 40mg now
    It is too early to draw any conclusions for this as fluoxetine can take quite a while to kick-in due to its very long half-life. It may take up to 12 weeks to get a positive response and even longer to get the full effects.

    and I am just wondering if it is possible I could still be feeling some withdrawal effects from coming of the ven and lowering the mirtazapine? I stopped ven completely 11 weeks ago.
    It is unlikely to be withdrawal from venlafaxine due to the fluoxetine, plus venlafaxine withdrawal symptoms tend to be most severe at the beginning and ease over the first month or so. Mirtazapine's most common withdrawal symptom is insomnia, however, it could be contributing to to the anxiety/OCD.
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Similar Threads

  1. Fluoxetine 40mg day 1
    By Jeancarlo123 in forum Fluoxetine / Prozac
    Replies: 0
    Last Post: 17-05-16, 22:10
  2. Help 40mg of fluoxetine
    By Glasgowkaren83 in forum General Anxiety / Generalised anxiety disorder (GAD)
    Replies: 1
    Last Post: 06-12-15, 03:09
  3. Citalopram 40mg not working so well, where next?
    By crumble in forum Citalopram / Celexa
    Replies: 1
    Last Post: 16-01-15, 00:02
  4. Fluoxetine 20mg - 40mg
    By AngelicSwallow in forum Fluoxetine / Prozac
    Replies: 3
    Last Post: 04-04-13, 00:47
  5. from 20mg to 40mg fluoxetine
    By Butterfly22 in forum Fluoxetine / Prozac
    Replies: 2
    Last Post: 12-08-11, 11:19

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •