Quote Originally Posted by Catkins View Post
I was dreading you saying that it would be working as well as it could right now, and this was as good as it's going to get.
There are no guarantees. The increased dose may not work, but the odds are in your favour.

I didn't think I could have a dose increase on promethazine. I thought 25mg would be the standard dose.
The recommended dose range for insomnia is 25-50mg. There isn't one for anxiety as this is an off-label use, but for most of its other indications the recommended daily doses are in the 6.75-75mg range and I don't see why this should be any different for anxiety. Promethazine has a fairly short half-life - 10-19 hours - so taking it once a day may not give adequate 24 hour relief.