Re: Promethazine
Originally Posted by
Catkins
.I'm sure I did read somewhere that you can build up a tolerance to it. If so would upping the dose help?
Promethazine is an antihistamine with some antipsychotic properties. As with most antihistamines, tolerance can build though it is usually slow to do so. I can't say whether you're developing a tolerance to it, or are experiencing break-through anxiety. It might even be a combination of both. Increasing the dose may help for a while, especially if it is break-through anxiety.
Well I rang the doctor - he said to carry on at the dose I'm on now but he's also prescribed propanolol.
Feeling a bit uncertain about what to do for the best.
Propranolol can be sedating as it blocks adrenaline, aka epinephrine, so may help. It also diminishes the adrenaline fuelled symptoms of the 'flight-or-fight' response which can ease anxiety.
Personally, I would ask for immediate release trazodone to replace both promethazine and propranolol as it has a proven track record for easing SSRI/SNRI induced insomnia. It is mostly prescribed just for that these days despite being an effective AD.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.