I appreciate that you cannot tolerate living with uncertainty. Neither can my adult children but there comes a stage where you have to accept that no one on earth can answer your questions nor can anyone satisfy your need to be given definitive boundaries as to when Covid will "end".
The fact now is that your wife is ill and her parents will expect you to care for her. This means putting her first. It will be hard for you to do this but you are her husband and she is relying on you. She won't want to hear about your worries. It's about her not you. You have to get through her illness without bemoaning the fact that you have lost 2 years of your life to Covid...We all have suffered, some much more than others but you won't be concerned about that of course.
i hope your wife is ok and soon over the worst of it. You'll survive, Phil...It's always the way.