SARS-CoV-2 is the cause of COVID-19 and is responsible for 175,541,600 confirmed cases and 3,798,361 deaths worldwide. There are upward of 220,000 cases daily (
www.who.com; accessed 14 June 2021). Most persons who contract COVID-19 survive their illness, but up to 70% of survivors have one or more symptoms lasting for 3 months or greater. Resting tachycardia, dyspnea, post-exercise exhaustion, sleep disturbance and fatigue are common, lingering symptoms—each could be explained by post-viral autonomic dysfunction. Comprehensive testing in experienced centers and clinical trials are needed to address a common barrier to full recovery in persons surviving COVID-19.