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Thread: 11weeks on Duloxetine still struggling

  1. #1
    Join Date
    Mar 2012
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    800

    11weeks on Duloxetine still struggling

    Hi All,

    This is my 2nd time on duloxetine. was on it from oct 19 to nov 20 going from 30mg up to 120mg. this time though, the main difference is that I am not on Lorazepam this time.my current NHS consultant wanted me off them so did a diazepam taper mar to aug 21. I'm hoping from what Ian(PDU) says about benzos blocking AD efficacy i have a better chance of them working this time. i have been on 60mg for 10 weeks and 90mg 10 days. since upping to 90mg my anxiety has been getting worse. waves of anxiety through my body. sweating palms.

    really frightened.

    any support would be greatly appreciated.

    Kind regards,

    Paul

  2. #2
    Join Date
    Jan 2017
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    3,158

    Re: 11weeks on Duloxetine still struggling

    Quote Originally Posted by Sober2000june View Post
    This is my 2nd time on duloxetine. was on it from oct 19 to nov 20 going from 30mg up to 120mg

    ...I'm hoping from what Ian(PDU) says about benzos blocking AD efficacy i have a better chance of them working this time.
    As I recall even 120mg didn't work that well, Paul.

    i have been on 60mg for 10 weeks and 90mg 10 days.
    Even without the BZD 60mg probably wasn't going to be enough given you were taking 120mg before with indifferent results. Plus, ADs tend to be less effective the second time with higher doses sometimes being necessary to achieve the previous levels of control. The initial side-effects can be different, or more severe too.

    since upping to 90mg my anxiety has been getting worse. waves of anxiety through my body. sweating palms.
    Heightened anxiety when first taking ADs, or after increasing the dose is quite common, unfortunately, and this is the most likely explanation. It should begin to diminish after a week or two, though side-effects can linger for some. Talk to your consultant about this as there are ways of easing the discomfort.

    BTW, what happened with trazodone?
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  3. #3
    Join Date
    Mar 2012
    Posts
    800

    Re: 11weeks on Duloxetine still struggling

    Hi Ian,

    I was on trazodone and quetiapine300mg. took 2 overdoses.

    tbh my psychiatrist doesnt come up with any ideas. its been me who suggested the meds.

    do you think im wasting my time with duloxetine?

    kind regards,
    Paul

  4. #4
    Join Date
    Jan 2017
    Posts
    3,158

    Re: 11weeks on Duloxetine still struggling

    Quote Originally Posted by Sober2000june View Post
    I was on trazodone and quetiapine300mg. took 2 overdoses.
    How much trazodone were you taking and how long had you been at that dose?

    tbh my psychiatrist doesnt come up with any ideas. its been me who suggested the meds.
    Then he/she isn't worth feeding, imo. Any chance of getting a different one?

    do you think im wasting my time with duloxetine?
    I can't predict the future, Paul. Duloxetine might kick-in overnight and greatly change your life, but your past history with it suggests this is a 50:50 chance at best.
    __________________
    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

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