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Thread: Trazadone 200mg and sleep

  1. #1
    Join Date
    Mar 2011
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    16

    Trazadone 200mg and sleep

    Hi, I increased to 200mg of this med 3 weeks ago and reduced co-prescribed venlafaxine to 75mg. My sleep quality has reduced with increased early morning waking and increased anxiety. Does anyone have any ideas about whether this is because traz is less sedating at this dose. Might things improve over time? Thanks for your thoughts 🙏

  2. #2
    Join Date
    Jan 2017
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    3,639

    Re: Trazadone 200mg and sleep

    Quote Originally Posted by biba View Post
    I increased to 200mg of this med 3 weeks ago and reduced co-prescribed venlafaxine to 75mg.

    ...Does anyone have any ideas about whether this is because traz is less sedating at this dose.
    Yes, trazodone becomes less sedating as the dose increases. But I suspect both the early awakening and heightened anxiety have more to do with the venlafaxine dose drop as both are common SSRI withdrawal symptoms and venlafaxine vies with paroxetine for being hard to quit.

    Might things improve over time?
    They most likely will as the withdrawal symptoms ease. You will likely also need a slightly higher trazadone dose for optimum results.
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    The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.

  3. #3
    Join Date
    Mar 2011
    Posts
    16

    Re: Trazadone 200mg and sleep

    Thanks so much, PDU. Your responses are always so helpful 🙏

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