Re: Ran out 18 days ago
Originally Posted by
Limeslime
I last took my fluoxetine 30mg on 8th June.
I have been taking fluoxetine for 2 years.
So this means I haven't taken any in nearly 3 weeks.
I feel ok. So far anyway.
Should I restart my fluoxetine or assume that it is out of my system now and I feel ok, therefore carry on without them?
Fluoxetine has a very long half-life, about 6 days for fluoxetine itself and up to 16 days for its active metabolite norfluoxetine, aka desmethylfluoxetine, which actually does most of the work. It takes about 4 weeks for all the fluoxetine to be eliminated and up to 80 days to get all of the metabolite out of your system. So at 3 weeks you still have about a quarter of the fluoxetine and around 85% of the norfluoxetine active.
Because of the long half-lives fluoxetine can be essentially self-tapering and some can quit it without significant withdrawal effects. But the operative word is "some". There are no guarantees and it usually takes a while for fluoxetine to begin working well again when it's reinstated. I urge you to discuss this with your GP asap.
__________________
The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.