I'm on Clomipramine. They have seemed to cure my panic attacks, but I still suffer from what I would describe as mild depression, probably due to the fact that I am a single mum of 3 working full-time with a newborn grandson as well (not sleeping very well at the moment).
Apart from the depression I feel pretty much ok and think I'm probably on a bit of a downer because sometimes I just crave adult conversation of an evening instead of doing all the homework and housework stuff. Don't get me wrong, I wouldn't change the kids for the world, but I have been on anti-deps for years and they have really been a life saver for me at times. I have been on Prozac in the past and was fine with them, and if a placebo was on the market that didn't have some of the side effects I would definitely be a guinea pig!
Like a lot of people have said, it depends on the individual. I have tried many different anti-deps over the past 25 years and some didn't agree with me at all, yet others worked brilliantly. I have noticed that nowadays though, rather than my GP go straight for his prescription book, he advises counselling and exercise as the first step. He advised me for CBT but the assessor said it wasn't really for me as I was suffering temporarily from health anxiety, which I seem to have under control now.
Good luck to everyone anyway. If the anti-deps work for you, I say continue!
Les