First I want to stress that everyone is different when it comes to medication. Having said that, I am on 40 mgs of Prozac and it is working great for me! I did find I had increased anxiety the first two to three weeks though, but I am so glad I stuck it out. It seems to take about 6 to 8 weeks to "really" work, but well worth the wait. I am somewhat med phobic, so starting a new medication for me is very hard. I was on Paxil for several years and it was wonderful, but for some reason stopped working. Then I was on Celexa which was great for the anxiety/panic but not great for depression (for me). But then again, I have a friend who swears by it. So it is really a "trial and error" sort of thing... medications. I'm just so grateful there are medications that work!!! Good luck to you!!!!