Anafaril so far

[Barnabas75]

Thanks PDU. I moved up to 75mgs today which I know is still a low dose but have had practically no side effects. Except a little sleepy. In your opinion should they rather be taken at night? The Doctor seemed to have no proplem with it. Compared to ssris this is a walk in the park.

[panic_down_under]

I moved up to 75mgs today which I know is still a low dose but have had practically no side effects. Except a little sleepy.

Anafranil is a fairly strong antihistamine so will produce some sedation. This does diminish a little over time, but probably won't completely go away. The TCA I take is still sedating after nearly 21 years, although admittedly I am on a very high dose and it is a more potent antihistamine than Anafranil.

It is still early days so you may yet experience some other side-effects. They are usually milder than those from SSRIs, however, as with everything about antidepressants, YMMV.

In your opinion should they rather be taken at night?

When taken for more than a week Anafranil plasma levels stabilize to a steady-state and then don't vary much across 24 hours so it probably won't make much difference, but give it a try anyway. The important thing is to pick a time of day when you can take it consistently.