Hi! I have never taken Effexor either, but think you should maybe talk to your doctor about increasing the dose as I don't think you are even at a therapuetic dose at 37.5mg. I'm totally the same when I get home from work, am mentally exhausted and just want to lay on the bed and recover from the day at work. I try to make myself sit out and watch television with my partner, cook dinner etc, because otherwise I know that depression will definately set in. If you accomplish even the smallest of tasks it can lift your mood. I know you really don't feel like it, but it does help. Hope you start to feel better soon. xx