Re: Starting at 50mg per day next week
Originally Posted by
irishman7
What are your thoughts on this medication will it be a life saver?
Pregabalin does essentially the same thing as benzodiazepines (BZDs), just from a different direction. BZDs work by increasing the infux of negatively charged ions into neurons making it harder for them to raise their internal voltages to the 'firing' threshold. Pregabalin (and gabapentin) achieve the same result by inhibiting the infux of positively charged calcium ions.
Like the BZDs tolerance can be an issue, although it is usually slower to begin, as are difficult withdrawals. If you read previous posts in this sub you'll see that not many are on pregabalin alone. Imho, if ADs work they are a better bet.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.
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