I tried 5 other meds - 4 ssri's (which made me ill) and lofepramine (which worked a little) until gp tried me on this 4 years ago. It works for me but everyone is different. It does give me yawning and constipation but on the whole it has kept me stable. Only on a low dose. I have gone very low and agitated this last two weeks though so going up to 30mg and then maybe higher if I need to as I hate feeling anxious and agitated, it makes me light headed panicky and tearful, so oping a higher dose will help and if it does I am happy to take it for life. Hate feeling like this. x