Quote Originally Posted by sparky10 View Post
Thanks pdu for your insightful reply. The amount of diazepam I was on was relatively low so not sure if this would affect neurogenesis with the length of time I was on the antidepressants. Tops 5mg
If taken daily that 5mg mounts up especially given the long diazepam half-life.

The nortriptyline didn’t suit me at all it made me very dissociated aswell as deer in the headlights syndrome. I definetely dont think norepinephrine is the answer as Cymbalta had similiar effects.
How long were you on nortriptyline and at what dose? Disassociation and the 'deer in headlight' feeling are not uncommon when first taking ADs, but it usually passes.

You've been on a lot of different ADs and it is unusual for all to produce completely negative results given the array of different receptor, transporter and neurotransmitter system effected. I wonder how much of the issues were created by the meds and how much by anxiety. An anxious mind is more than capable of producing the most unpleasant side-effects imaginable.