Imipramine, have I made the right choice?

[panic_down_under]

Apparently according to the doctor I spoke to they follow the NICE guidelines.

The BNF dosing guideline I link to earlier suggests they aren't as the Formulary is produced by NICE.

I can't remember so well when I was on duloxetine, if I remember correctly I spoke to a doctor that said it sounded like it was making me depressed however I was going through a hard time at work and had a bereavement around that time.

Some do have paradoxical reactions to an AD and become more depressed so it is possible the doctor was correct.

I do remember being spaced out and lethargic as hell a lot on it plus the usual sexual dysfunction and emotional blunting. I think if they won't budge on the 150mg imipramine it might be worth trying it again, since a lot of those stressors I've had at the time are resolved.

If 150mg works and 100mg doesn't then they'd be crazy to insist you return to the lower dose. Get another opinion if it comes to that.