Hi again to all, I have been on Citalopram since the end of December, moving to 20 mg mid January and 30 mg mid-February. While citalopram initially helped out, it does not seem to be doing much anymore. It might be due to life circumstances--i have recently started a new job and got out of 2 year relationship. However, I generally feel bad the majority of the time. My doctor said I could try 40 mg out for a bit to a see if it helps or switch meds. I am inclined to try 40 mg because switching meds seems like starting all over. Have I given it enough time? Has anyone noticed a significant difference by moving from 30 to 40? Thank you, Daryl.