I have an eye condition that flares up with excess cortisol (they think!) and I came across evidence that duloxetine lowers cortisol in the short term, whereas Venlafaxine might raise it. That was the main reason for me requesting the Duloxetine.

Venlafaxine acts as an SSRI at lower doses apparently (below 150mg?), but duloxetine acts as a SNRI at all doses.

How are you finding the Venlafaxine?