How does this compare to SNRI's that work on both serotonin and norepinephrine? NRI's are aimed at norepinephrine only but have a small effect on serotonin as well.
Isn't this the argument behind SNRI's? SNRI's have only been found marginally more effective than the older SSRI's. NRI's have been found more effective in some studies but there seems to be some concern of the validity of those studies.
Maybe we can all end up on SNDRI's and get dopamine in there too?!
Where does hyperprolactinaemia come into this? Are you suggesting that dopamine levels have been inhibited? In which case wouldn't it be a better alternative to boost dopamine levels naturally instead of using cabergoline to provide a potent boost which is 'off label' in some countries for use alongside SSRI's? Maybe try natural increases of supplementation of tyrosine and L-phenylalanine?
Could it even be that GABA levels are too high since that inhibits dopamine?
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