I was looking into this earlier. Sertraline on its own can increase the chance of gastrointestinal bleeding, so can ibuprofen or aspirin. Take them together and you are just asking for trouble! It's just not worth finding out for yourself. Play it safe and stick to paracetamol.
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Trish I feel the same on sertraline. No energy, no drive, nothing. I've also been really poorly due to taking ibuprofen with sertraline for several weeks. I stored away my ibuprofen pills earlier not to be used again while I'm on sertraline. My symptoms have been very similar to someone with severe iron deficiency due to blood loss.