No
How do you draw that conclusion?
As I said earlier is this thread, there is a lot of ignorance about tricyclics.
Credible Meds maintains the QTc drug data base
for the FDA.
Their advice for amitriptyline is:
For nortriptyline:
This is the same rating as for fluoxetine, fluvoxamine, paroxetine and sertraline.
OTOH, citalopram (and escitalopram) has the more serious warning:
The CredibleMeds lists imipramine as:
which, as above, puts it on par with most of the SSRIs and much better than citalopram and escitalopram.
So challenging a claim which seems incorrect is "jump[ing] up and down"?
And here's some more selected info:
Carrière I, 2017,
Antidepressant use and cognitive decline in community-dwelling elderly people"
Podewils LJ, 2002,
"Tricyclic antidepressants and cognitive decline.":
OTOH, there is
some evidence TCAs reduce dementia risk.
Yes, mostly imipramine for the first 10 years at doses of 300-350mg/day for most of that period, the last 21 years I've continually been on 225mg dosulpin, aka dotheipin, which is the most cardio toxic antidepressant by a considerable margin. Despite being under greater than normal pressure as a result of having had a lung removed, my almost 70yo heart remains fine. Nor has 30 years of TCA use at very high doses addled my brain.
---------- Post added at 11:50 ---------- Previous post was at 09:50 ----------
Thank you for the vote of confidence. I don't take these things personally. I've been around support groups long enough to know that things can be misinterpreted, even with the use of emoticons, etc. All just part of the rich tapestry of life.