Re: Ah god here goes again...
Originally Posted by
Benjammin69
Hi Ian hope your well mate.
And me, you. I'm still fogging the mirror every morning which at my age is always a positive.
Trying to break in a new (to me) GP atm which is proving harder than it should be. Youngsters these days...
Do you have an idea of when I would feel withdrawals if I was to? I’m on day 5 and nothing yet really I know withdrawal is as much psychological and physiological so don’t want to trigger anything but at the moment my initial drop has been pretty comfortable - less appetite and the sh..its is all lol
The mirtazapine half-life is 20-40 hours so it takes 4-8 days for plasma levels to stabilize to a steady-state after a dose reduction (or increase). Generally withdrawal symptoms begin before that happens so if a fast metaboliser you'd already have begun to feel something and if a slow one then in the next day, or two. However, as per an earlier post, I expect any symptoms to be muted because of the quetiapine.
My best tip is to not get hung up about this as psychology can be an even bigger driver of withdrawal symptoms than the physiological impact. There have been severe studies of various anxiety meds where merely telling those taking them that the dose has been reduced triggers the full catastrophe in many even though the dose remained unchanged. An anxious mind can be truly frightening in the intensity if what it can create from nothing if given half an excuse.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.