Re: Imipramine or Clomipramine
Originally Posted by
SideFX
I am a bit fuzzy bout the buspar, could of been Wellbutrin that made me so angry. I took it with venlafaxine at the time.
Bupropion (Wellbutrin) is a very stimulating AD so would be more likely to trigger anger I would have thought, although it is a listed side-effect of both meds. Not a med most with anxiety can tolerate as it can almost literally have them climbing the walls, but small adjuvant doses to counter AD induced weight gain, or for sexual dysfunction can be useful, however, buspirone is often effective for the latter so the better initial option.
I personally find that the CBT and other cognitive therapies are of no use to me...
Unfortunately, therapy didn't help me either, but I did enjoy the sessions.
I have started trying CBD Oil and don’t know if it’s placebo effect, but it does help...
It can be, however, cannabis isn't as THC has the same deleterious effects on hippocampal neurons as alcohol, BZDs and cortisol.
I need to be careful though as my second dose of Pregabalin with Diazipam can knock me out like a tranqulliser dart. I take them 6 hours apart and this has always been the case. It’s as if the peak is delayed for several hours and as I’m coming down of it I can feel it bad.
Interesting. The amount of diazepam in your system wouldn't vary much across 24 hours. Pregabalin's may if you're a fast metaboliser because of its short half life
I was thinking of trying again to taper the Pregabalin, as I’ve tried and failed twice
The problem can be that short half-life because it can drop out of the system very quickly especially at the lower doses which may set up a roller-coaster effect which many find very disturbing. Upping the diazepam dose may help, but your GP may take some convincing given you're on a largish dose already.
I totally agree with you in regards of the vortioxatine, with the M.O. of drop to 5mg and cross taper for 2 weeks with a small dose of imipramine. I so need all of the above to work out for me, as I have so much hanging on it...My work and my livelihood!!!!!
You need to get your GP's and particularly your psychiatrist's inputs on this too. On paper it should be fine, but these things all come down to YMMV, and they are better placed to foresee any likely pitfalls based on your general well-being and history.
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The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.