Re: Venlafaxine again
Originally Posted by
Enola79
I am terrible at getting my meds so at times I do have to go without. I DO NOT RECOMEND THIS. I can't shout it enough. The withdrawal from this sends me over the top.
Withdrawal is not the only potential problem with missing doses. There is evidence antidepressants, especially the SSRIs, and despite the claims venlafaxine is only a SSRI, not SNRI, may become progressively less effective every time they are stopped and restarted, often requiring higher doses to achieve the previous level of control, or not working at all (see: Bosman RC, 2018; Amsterdam JD, 2016; Amsterdam JD, 2009; Amsterdam JD, 2009; Leykin Y, 2007; Paholpak S, 2002).
Missing a dose or two once in a blue moon is unlikely to be significant, but often skipping them for days at a time could be.
__________________
The opinions expressed above are based on my observations and, where applicable, interpretation of cited data and are general in nature. Consult your physician before acting on anything stated.